Articles Covering the Antibiotic and Antibacterial
Properties of Turmeric / Curcumin

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

- Rai, Dipti; Singh, Jay Kumar; Roy, Nilanjan; Panda, Dulal. School of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai, India. Biochemical Journal (2008), 410(1), 147-155.

Scientific Essence: The authors studied the antibacterial properties of curcumin. It has been shown that curcumin has antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus. The authors have proposed a mechanism for the antibacterial activity of curcumin. They suggest that it targets FtsZ protofilaments.


In-vitro antimicrobial activity of the ground rhizome, curcuminoid pigments and essential oil of Curcuma longa L

- Peret-Almeida, Lucia; Naghetini, Cristina da Cunha; Nunan, Elziria de Aguiar; Junqueira, Roberto Goncalves; Gloria, Maria Beatriz Abreu. Ciencia e Agrotecnologia (2008), 32(3), 875-881

Scientific Essence: The authors found that the essential oil of turmeric inhibited the growth of several bacteria such as E.Subtilis, S. choleraesuis and E. Coli. The effectiveness was comparable to that of the traditional antibiotics chloramphenicol and amphotericin. The authors conclude that the essential oil of turmeric is a promising antimicrobial agent.


Chemical constituents and biological activities of turmeric (Curcuma longa L.)

- Niranjan, Abhishek; Prakash, Dhan. Nutraceutical Chemistry, National Botanical Research Institute, Lucknow, India. Journal of Food Science and Technology (2008), 45(2), 109-116

Scientific Essence: The authors describe the various therapeutic effects of curcumin including its antibacterial and antiparasitic properties.


Turmeric (curcuma longa): a valuable traditional medicine

- Kumar, Vimal. Pharmacognosy Division at Institute of Pharmacy, Nirma University of Science and Technology, Ahmedabad, India. Pharma Review (2006), 4(24), 77-80

Scientific Essence: This article describes the use of turmeric in the traditional medical systems including Ayurveda, Unani and Siddha. It covers the various therapeutic effects of turmeric including its use as an anti-bacterial, anti-inflammatory and hepatoprotective agent.


Curcuma longa L. Constituents Inhibit Sortase A and Staphylococcus aureus Cell Adhesion to Fibronectin

- Park, Byeoung-Soo; Kim, Jae-Gyu; Kim, Mi-Ran; Lee, Sung-Eun; Takeoka, Gary R.; Oh, Ki-Bong; Kim, Jeong-Han. Journal of Agricultural and Food Chemistry (2005), 53(23), 9005-9009

Scientific Essence: This study covers the mechanism of action of action of turmeric as an antibacterial agent against S. aureus. The authors found that turmeric is a potent inhibitor of the bacterial surface protein sortase A.


Antimicrobial sesquiterpenoids and diarylheptanoid from Curcuma domestica

- Ragasa, Consolacion Y.; Laguardia, Marisol A.; Rideout, John A. ACGC Chemical Research Communications (2005), 18 21-24

Scientific Essence: In this study, the researchers isolated various compounds in turmeric (curcumin (I), bisacurone (II), a mixt. of ar-turmerone (III), ?-turmerone (IV), and ?-turmerone (V), and ar-curcumyl alc. (VI). ) and studied their antibacterial and antifungal activities. They observed that compounds II-VI have antifungal activity against A.niger and that III-VI have antibacterial activity against P. aeruginosa.


Curcumin blocks NF-B and the motogenic response in Helicobacter pylori-infected epithelial cells

- Foryst-Ludwig, Anna; Neumann, Manfred; Schneider-Brachert, Wulf; Naumann, Michael. Biochem Biophys Res Commun. (2004), 316(4), 1065-1072

Scientific Essence: The authors have performed experiments that support the use of curcumin as a attractive therapeutic candidate against inflammatory reaction triggered by the bacteriaHeliobacter pylori.